Human seminal plasma anaphylaxis (HSPA): case report and literature review

Allergy. 1995 Sep;50(9):747-50. doi: 10.1111/j.1398-9995.1995.tb01218.x.


Human seminal plasma anaphylaxis (HSPA) is rare but may be life-threatening. The antigen or antigens involved in these reactions reside in a glycoprotein fraction of human seminal plasma (HSP). We report a woman who experienced HSPA. Literature on the subject is reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anaphylaxis / etiology*
  • Anaphylaxis / immunology
  • Coitus
  • Female
  • Humans
  • Immunoglobulin E / analysis
  • Lymphocyte Activation
  • Semen / immunology*
  • Skin Tests


  • Immunoglobulin E