A new family of lipolytic plant enzymes with members in rice, arabidopsis and maize

FEBS Lett. 1995 Dec 27;377(3):475-80. doi: 10.1016/0014-5793(95)01405-5.


We have noted a striking similarity between the sequences of proteins in a novel family of lipases we recently reported [Upton, C. and Buckley, J. T. (1995) Trends Biol. Sci. 20, 178-9] and more than 120 sequences from the database of Expressed Sequence Tags (dbEST) which correspond to at least 30 unique genes from arabidopsis, rice and maize. A cDNA (Arab-1) corresponding to one of these sequences was isolated, sequenced and translated. There was significant similarity to sequences in the new lipase family over the entire open reading frame of Arab-1 and when expressed in E. coli, the gene product was lipolytic. Arab-1 and genes for some of the other plant proteins appear to be differentially expressed. They may play a role in the regulation of lipid metabolism during plant development.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / enzymology
  • Arabidopsis / genetics
  • Base Sequence
  • Butyrates / metabolism
  • DNA, Complementary / genetics
  • Gene Expression
  • Lipase / genetics*
  • Lipolysis / genetics*
  • Molecular Sequence Data
  • Oryza / enzymology
  • Oryza / genetics
  • Plants / enzymology*
  • Plants / genetics
  • RNA, Messenger / analysis
  • Sequence Homology, Amino Acid
  • Tissue Distribution
  • Transcription, Genetic
  • Zea mays / enzymology
  • Zea mays / genetics


  • Butyrates
  • DNA, Complementary
  • RNA, Messenger
  • 4-nitrophenyl butyrate
  • Lipase

Associated data

  • GENBANK/U38916