Epidemiological analysis of strains of methicillin-resistant Staphylococcus aureus (MRSA) infection in the nursery; prognosis of MRSA carrier infants

J Hosp Infect. 1995 Oct;31(2):123-34. doi: 10.1016/0195-6701(95)90167-1.

Abstract

Forty-five neonates who carried methicillin-resistant Staphylococcus aureus (MRSA) were studied. Retrospective molecular analysis using pulsed-field gel electrophoresis showed three separate MRSA epidemics in the nursery. Strains of MRSA isolated from the neonates were also isolated from the hospital environment and health care providers. Clinical manifestations included skin pustules (eight patients), conjunctivitis (four patients), or other minor infections (two patients). No neonate developed systemic infection. The prevalence of MRSA decreased with age. At one year, three (14.3%) of 21 infants that had carried MRSA at six days remained carriers and only two (1.1%) of 180 infants in a control 'S. aureus-negative at six days' group carried MRSA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Distribution
  • Carrier State / epidemiology*
  • Carrier State / microbiology
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks*
  • Electrophoresis, Gel, Pulsed-Field
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Infection Control
  • Japan / epidemiology
  • Methicillin Resistance*
  • Nurseries, Hospital
  • Prevalence
  • Prognosis
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus* / classification