Why does Escherichia coli recycle its cell wall peptides?

Mol Microbiol. 1995 Aug;17(3):421-6. doi: 10.1111/j.1365-2958.1995.mmi_17030421.x.

Abstract

This review discusses the phenomenon of recycling of cell wall peptides. It is a major, though non-essential, pathway of the cell and is required for induction of beta-lactamase. Consequently, the recycling pathway is viewed as a possible signalling vehicle, informing the cell of the condition of the murein sacculus, an essential structure existing outside the cell itself. As the study of this phenomenon is in its infancy, several speculations are offered for a possible regulatory function.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Carbohydrate Sequence
  • Cell Wall / chemistry
  • Cell Wall / metabolism
  • Enzyme Induction
  • Escherichia coli / genetics
  • Escherichia coli / metabolism*
  • Gram-Positive Bacteria / metabolism
  • Membrane Proteins / metabolism
  • Membrane Transport Proteins*
  • Molecular Sequence Data
  • N-Acetylmuramoyl-L-alanine Amidase / metabolism
  • Peptides / genetics
  • Peptides / metabolism*
  • Peptidoglycan / chemistry
  • Peptidoglycan / genetics
  • Peptidoglycan / metabolism
  • beta-Lactamases / biosynthesis

Substances

  • AmpG protein, Bacteria
  • Bacterial Proteins
  • Membrane Proteins
  • Membrane Transport Proteins
  • Peptides
  • Peptidoglycan
  • AmpD protein, Bacteria
  • N-Acetylmuramoyl-L-alanine Amidase
  • beta-Lactamases