Quality of life in chronic fatigue syndrome

Soc Sci Med. 1995 Nov;41(10):1367-72. doi: 10.1016/0277-9536(95)00124-p.


Whilst the debilitating fatigue experienced in patients suffering from Chronic Fatigue Syndrome (CFS) results in a subjective marked impairment in functioning, little research has investigated the impact of this disorder on quality of life. Forty-seven subjects with a confirmed diagnosis of CFS and 30 healthy controls were compared using the Sickness Impact Profile (SIP). A subgroup of subjects were interviewed regarding the impact CFS has had on their social and family relationships, work and recreational activities. Results from both the SIP and the interview revealed that CFS subjects had significantly impaired quality of life, especially in areas of social functioning. These findings highlight the importance of addressing the social isolation and loss of role functioning experienced by CFS sufferers.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Case-Control Studies
  • Discriminant Analysis
  • Employment
  • Fatigue Syndrome, Chronic* / complications
  • Fatigue Syndrome, Chronic* / psychology
  • Female
  • Health Status
  • Humans
  • Interpersonal Relations
  • Male
  • Quality of Life*
  • Recreation
  • Social Adjustment