The G-box: a ubiquitous regulatory DNA element in plants bound by the GBF family of bZIP proteins

Trends Biochem Sci. 1995 Dec;20(12):506-10. doi: 10.1016/s0968-0004(00)89118-5.


The G-box (CACGTG) is a ubiquitous, cis-acting DNA regulatory element found in plant genomes. Proteins known as G-box factors (GBFs) bind to G-boxes in a context-specific manner, mediating a wide variety of gene expression patterns. We suggest that, as for many biological systems, different combinations of these common elements can lead to diversity and specificity in the regulation of plant gene expression.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA, Plant / chemistry*
  • DNA-Binding Proteins / chemistry
  • DNA-Binding Proteins / metabolism*
  • Gene Expression Regulation, Plant
  • Leucine Zippers
  • Molecular Sequence Data
  • Plants / genetics*
  • Regulatory Sequences, Nucleic Acid*


  • DNA, Plant
  • DNA-Binding Proteins