Transcriptional coactivators in yeast and beyond

Trends Biochem Sci. 1995 Dec;20(12):517-21. doi: 10.1016/s0968-0004(00)89120-3.


Coactivators are a novel class of transcriptional activator required at many eukaryotic promoters. Several coactivators have now been isolated, their identification often facilitated by genetic studies in yeast. Some of the proposed mechanisms of coactivator function may help explain synergy between transcriptional activators at eukaryotic promoters.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Drosophila
  • Promoter Regions, Genetic
  • Saccharomyces cerevisiae / genetics*
  • Trans-Activators* / physiology
  • Transcription Factors
  • Transcription, Genetic*


  • Trans-Activators
  • Transcription Factors