Signal Transduction of Beta-Catenin

Curr Opin Cell Biol. 1995 Oct;7(5):634-40. doi: 10.1016/0955-0674(95)80104-9.

Abstract

Beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in beta-catenin signaling.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Adhesion / physiology
  • Cell Division / physiology
  • Cytoskeletal Proteins / physiology*
  • Signal Transduction / physiology*
  • Trans-Activators*
  • beta Catenin

Substances

  • Cytoskeletal Proteins
  • Trans-Activators
  • beta Catenin