Helicobacter pylori infection and chronological extension of atrophic gastritis

Eur J Gastroenterol Hepatol. 1995 Aug;7 Suppl 1:S11-5.

Abstract

Objectives: To determine the relationship between Helicobacter pylori infection and chronological extension of atrophic gastritis.

Patients and methods: We studied 137 non-ulcer patients. The extent of atrophic gastritis was assessed endoscopically and scored on a scale of 1-6 (endoscopic score) using the atrophic pattern system. H. pylori infection was assessed by enzyme-linked immunosorbent assay with serum anti-H. pylori immunoglobulin G. The correlation between patient age and endoscopic score was determined for H. pylori-positive and -negative patients.

Results: A positive correlation between age and extent of atrophic gastritis was found in both H. pylori-positive and -negative patients. In groups of patients aged 20-29 and 30-39 years, those with H. pylori had more extensive atrophic gastritis than those without H. pylori.

Conclusions: Chronological extension of atrophic gastritis was found in patients with and without H. pylori infection.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Female
  • Gastritis, Atrophic / immunology
  • Gastritis, Atrophic / microbiology*
  • Gastritis, Atrophic / pathology
  • Gastroscopy
  • Helicobacter Infections / complications*
  • Helicobacter Infections / immunology
  • Helicobacter Infections / pathology
  • Helicobacter pylori* / immunology
  • Humans
  • Immunoglobulin G / blood*
  • Male
  • Middle Aged
  • Time Factors

Substances

  • Immunoglobulin G