Antithrombotic benefits and hemorrhagic risks of direct thrombin antagonists

MeSH terms

• Amino Acid Sequence
• Animals
• Antithrombins / administration & dosage
• Antithrombins / adverse effects
• Antithrombins / therapeutic use*
• Blood Platelets / physiology
• Hemorrhage / chemically induced*
• Hirudin Therapy
• Hirudins / adverse effects
• Hirudins / analogs & derivatives
• Humans
• Molecular Sequence Data
• Papio
• Peptide Fragments / adverse effects
• Peptide Fragments / therapeutic use
• Platelet Aggregation Inhibitors / adverse effects
• Platelet Aggregation Inhibitors / therapeutic use*
• Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors
• Platelet Glycoprotein GPIIb-IIIa Complex / physiology
• Primates
• Recombinant Proteins / adverse effects
• Recombinant Proteins / therapeutic use
• Thrombin / physiology
• Thrombosis / drug therapy*