Handwipe sampling and analysis procedure for the measurement of dermal contact with pesticides

Arch Environ Contam Toxicol. 1996 Jan;30(1):132-8. doi: 10.1007/BF00211339.


A handwipe sampling and analysis procedure was developed for the measurement of dermal contact to pesticides. This procedure utilizes cellulose dressing sponges wetted with 2-propanol. A two-step wiping procedure is described that ensures that the entire hand is sampled. Removal efficiency experiments show that dry residues of the pesticides chlorpyrifos and pyrethrin I are quantitatively removed from hands immediately following contact. Results suggest that the procedure may remove pesticide residues that are deeply embedded in the skin and not removed by soap-and-water washing. Extraction efficiency studies for 29 other pesticides show that the proposed extraction method may be applicable for a wide range of pesticides including phenoxy-acid herbicides. Field testing of the procedure indicates that it is easily implemented by sampling personnel and readily accepted by children.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Child
  • Child, Preschool
  • Chlorpyrifos / analysis
  • Environmental Exposure
  • Fresh Water
  • Gas Chromatography-Mass Spectrometry
  • Hand
  • Humans
  • Insecticides / analysis*
  • Occupational Exposure
  • Pyrethrins / analysis
  • Skin / chemistry*
  • Skin / pathology


  • Insecticides
  • Pyrethrins
  • Chlorpyrifos
  • pyrethrin I