Bone mineral status in preterm-born children: assessment by dual-energy X-ray absorptiometry

Biol Neonate. 1995;68(4):254-8. doi: 10.1159/000244243.

Abstract

To elucidate the long-term consequences of osteopenia of prematurity, lumbar spinal bone mass was measured in 21 preterm-born children aged 3-4 years by dual-energy X-ray absorptiometry. Their mineral intake remained low during early life, and all 11 infants previously studied were osteopenic at term postconception. At the age of 3-4 years, however, all 21 children were found to have normal bone mineral content and density with slightly elevated serum osteocalcin levels. Our results show that in preterm-born children spontaneous resolution of lumbar spinal osteopenia occurs during early childhood.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon / standards*
  • Body Weight / physiology
  • Bone Density / physiology*
  • Bone Diseases, Metabolic / blood
  • Bone Diseases, Metabolic / physiopathology
  • Calcium / blood
  • Child, Preschool
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature / physiology*
  • Infant, Premature, Diseases / blood
  • Infant, Premature, Diseases / physiopathology
  • Lumbar Vertebrae / physiology
  • Male
  • Osteocalcin / blood
  • Remission, Spontaneous

Substances

  • Osteocalcin
  • Calcium