P300 differences between sinistrals and dextrals

Brain Res Cogn Brain Res. 1995 Oct;2(4):277-82. doi: 10.1016/0926-6410(95)90019-5.


The P3(00) event-related potential (ERP) was elicited in 20 left- and 20 normal right-handed young adult male subjects using a simple visual stimulus discrimination task. For left-compared to right-handed subjects, P3 amplitude was larger at anterior electrode sites for the target stimuli and larger overall for the novel visual stimuli; P3 latency was shorter for left-compared to right-handers for the target stimuli. The N1, P2, and N2 components demonstrated similar handedness effects. The relationships of ERP amplitude and handedness to anatomical variables and cognitive factors are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Discrimination Learning / physiology*
  • Electric Stimulation
  • Evoked Potentials / physiology*
  • Functional Laterality / physiology*
  • Humans
  • Male
  • Pattern Recognition, Visual / physiology*
  • Reaction Time / physiology