Antigens from Taenia crassiceps cysticerci used in complement fixation, enzyme-linked immunosorbent assay, and western blot (immunoblot) for diagnosis of neurocysticercosis

J Clin Microbiol. 1995 Dec;33(12):3324-5. doi: 10.1128/jcm.33.12.3324-3325.1995.

Abstract

Antigens from Taenia solium cysticerci for the immunodiagnosis of cysticercosis are scarce and difficult to obtain. We studied the reliability of antigens from Taenia crassiceps cysticerci as a substitute for those from T. solium in three diagnostic tests: complement fixation, enzyme-linked immunosorbent assay, and Western blot (immunoblot). Precision rates of the three tests of 93, 99, and 96%, respectively, were found. Cysticerci from T. crassiceps can be easily obtained in large quantities and can be effectively used for the diagnosis of human neurocysticercosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Helminth / cerebrospinal fluid
  • Antigens, Helminth*
  • Blotting, Western / methods
  • Brain Diseases / diagnosis*
  • Brain Diseases / immunology
  • Complement Fixation Tests / methods
  • Cysticercosis / diagnosis*
  • Cysticercosis / immunology
  • Cysticercus / immunology*
  • Enzyme-Linked Immunosorbent Assay / methods
  • Evaluation Studies as Topic
  • Humans
  • Immunologic Tests / methods*

Substances

  • Antibodies, Helminth
  • Antigens, Helminth