Corynebacterium argentoratense sp. nov., from the human throat

Int J Syst Bacteriol. 1995 Jul;45(3):533-7. doi: 10.1099/00207713-45-3-533.

Abstract

A new Corynebacterium species, Corynebacterium argentoratense was isolated from the throats of four human patients. It is characterized by the presence of chemotype IV, a cell wall, corynomycolic acids, and a G+C content ranging from 60 to 61 mol%. Strains belonging to this species exhibit high levels of DNA relatedness as determined by DNA-DNA hybridization experiments (S1 nuclease procedure) but no close DNA relatedness with related Corynebacterium species. Phylogenies based on comparative analyses of nearly complete small-subunit rDNA sequences confirmed the inclusion of this new species within the genus Corynebacterium and grouped it in a cluster with C. diphtheriae, C. ulcerans, C. pseudotuberculosis, and C. kutscheri. PCR experiments revealed an absence of the gene coding for diphtheria toxin. This new species can be identified by its mycolic acid pattern, fermentation of sugars, and enzymatic activities. Strain IBS B10697 (CIP 104296) is the type strain of C. argentoratense.

MeSH terms

  • Amidohydrolases / metabolism
  • Base Composition
  • Base Sequence
  • Corynebacterium / classification*
  • Corynebacterium / genetics
  • Corynebacterium / isolation & purification
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • Diphtheria Toxin / genetics
  • Diphtheria Toxin / isolation & purification
  • Glucose / metabolism
  • Humans
  • Molecular Sequence Data
  • Mycolic Acids / chemistry
  • Nucleic Acid Hybridization
  • Pharynx / microbiology*
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Homology, Nucleic Acid

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • Diphtheria Toxin
  • Mycolic Acids
  • RNA, Ribosomal, 16S
  • Amidohydrolases
  • pyrazinamide deamidase
  • Glucose

Associated data

  • GENBANK/X83955