Diffuse cutaneous infection caused by a presumed monoxenous trypanosomatid in a patient infected with HIV

Trans R Soc Trop Med Hyg. Nov-Dec 1995;89(6):644-6. doi: 10.1016/0035-9203(95)90427-1.


A patient infected with human immunodeficiency virus developed a diffuse cutaneous nodular syndrome. The parasite isolated from a skin nodule was studied by isoenzymatic characterization and transmission electron microscopy of both culture forms and those in the patient's skin biopsy. The parasite's ultrastructure was that of a typical member of the family Trypanosomatidae, but it differed isoenzymatically from all 'new and 'old World' species of Leishmania, Trypanosoma and Sauroleishmania. We believe that it was a (presumably) monoxenous 'lower trypanosomatid.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / pathology
  • Adult
  • Animals
  • HIV-1
  • Humans
  • Male
  • Microscopy, Electron
  • Protozoan Infections / complications*
  • Protozoan Infections / pathology
  • Skin / parasitology
  • Skin / ultrastructure
  • Skin Diseases, Parasitic / complications*
  • Skin Diseases, Parasitic / pathology
  • Trypanosomatina / classification
  • Trypanosomatina / ultrastructure*