The capacity to transport potassium influences sodium tolerance in Saccharomyces cerevisiae

FEMS Microbiol Lett. 1996 Jan 15;135(2-3):157-60. doi: 10.1111/j.1574-6968.1996.tb07982.x.


The capacity to transport potassium and to discriminate between the different alkali cations has been found to affect sodium tolerance in Saccharomyces cerevisiae. Mutants with a defective capacity to transport K+ were more sensitive to high concentrations of Na+ because they accumulated more Na+ and less K+ than wild-type cells which showed high discrimination between K+ and Na+.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carrier Proteins / genetics
  • Cation Transport Proteins*
  • Fungal Proteins / genetics
  • Ion Transport
  • Membrane Proteins / genetics
  • Mutation
  • Potassium / metabolism*
  • Rubidium / metabolism
  • Saccharomyces cerevisiae / drug effects
  • Saccharomyces cerevisiae / metabolism*
  • Saccharomyces cerevisiae Proteins*
  • Sodium / pharmacology*


  • Carrier Proteins
  • Cation Transport Proteins
  • Fungal Proteins
  • Membrane Proteins
  • Saccharomyces cerevisiae Proteins
  • TRK2 protein, S cerevisiae
  • TRK1 protein, S cerevisiae
  • Sodium
  • Rubidium
  • Potassium