Cystic fibrosis. Gastrointestinal complications and gene therapy

Pediatr Clin North Am. 1996 Feb;43(1):157-96. doi: 10.1016/s0031-3955(05)70401-6.


The gastrointestinal and nutritional complications of cystic fibrosis are diverse. As longevity improves in patients with cystic fibrosis, management of these complications is becoming increasingly important . This article provides overviews of the molecular aspects of the pathogenesis of cystic fibrosis, the current status of gene therapy, and a review of the gastrointestinal manifestations and nutritional care.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cystic Fibrosis* / complications
  • Cystic Fibrosis* / diagnosis
  • Cystic Fibrosis* / genetics
  • Cystic Fibrosis* / therapy
  • Gastrointestinal Diseases / genetics*
  • Genetic Therapy* / methods
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Phenotype