Gastrospirillum hominis-associated chronic active gastritis

Pediatr Pathol Lab Med. May-Jun 1995;15(3):429-35. doi: 10.3109/15513819509026978.


A 16-year-old Caucasian male presented with nausea, vomiting, and abdominal pain. Endoscopy revealed erythematous antral mucosa with four discrete gastric ulcers. Biopsies showed multiple spiral organisms, 4-6 microns in length, lying in the mucous layer on the surface. The organisms were strongly Giemsa positive and weakly CLOtest positive. They did not stain with Warthin-Starry silver or Gram-Weigert stains. Electron microscopy revealed fragments of Gastrospirillum hominis, with its characteristic spiral shape and length of 4 microns in the plane of section. We believe that this is one of the first reported pediatric cases in North America.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bacterial Infections / pathology*
  • Chronic Disease
  • Gastritis / microbiology
  • Gastritis / pathology*
  • Helicobacter heilmannii* / ultrastructure
  • Humans
  • Male
  • Pyloric Antrum / microbiology
  • Pyloric Antrum / pathology