Lack of ventricular remodeling in non-Q-wave myocardial infarction

Am Heart J. 1996 Mar;131(3):466-71. doi: 10.1016/s0002-8703(96)90524-4.


We prospectively examined 45 patients with serial echocardiography to measure left ventricular end-diastolic volume index within 1 week and at 6 weeks after infarction. Left ventricular volume increased in patients with Q-wave infarction but not in those with non-Q or in control patients without recent infarction. Peak creatine phosphokinase levels were greater in Q-wave infarction compared with those in non-Q-wave infarction. There was a strong correlation between the change in the left ventricular end-diastolic index and the peak creatine phosphokinase level. After correcting for infarct size, there was still a difference between the two groups. Our data indicate that ventricular remodeling does not occur in non-Q-wave as opposed to Q-wave infarcts, and this may be related both to the limited amount of myocardial necrosis and to the nontransmural extent of the necrosis.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chi-Square Distribution
  • Echocardiography
  • Electrocardiography
  • Female
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / physiopathology*
  • Prospective Studies