The implications of depression for pain and disability in rheumatoid arthritis

Arthritis Care Res. 1995 Dec;8(4):279-83. doi: 10.1002/art.1790080412.


Depression in rheumatoid arthritis (RA) affects many, but by no means all, persons with the disease. There is evidence that depression bears a significant relationship to pain in RA, although the causal direction is not entirely clear. Likewise, there is strong evidence that depression is a major contributor to the RA disability. Therefore, prevention, early diagnosis, and aggressive treatment of depression are needed to minimize the disability associated with RA.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / psychology*
  • Depressive Disorder / etiology*
  • Depressive Disorder / prevention & control
  • Disabled Persons* / psychology
  • Humans
  • Pain / complications
  • Pain / psychology*