Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media

Eur J Clin Microbiol Infect Dis. 1995 Oct;14(10):908-11. doi: 10.1007/BF01691499.


A patient with a cholesteatoma secondary to chronic suppurative otitis media developed infective complications including cerebellar and cerebello-pontine abscesses. Burkholderia cepacia was isolated from ear swabs, infected tissue and surgical pus on five occasions over a six-month period. Despite exhibiting three different antibiotic susceptibility profiles, all five isolates were confirmed as clonally indistinguishable by pulsed-field gel electrophoresis. To the best of the authors' knowledge there are no previous reports of Burkholderia cepacia causing infection of the adult central nervous system.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Abscess / etiology*
  • Brain Abscess / therapy
  • Burkholderia cepacia / drug effects
  • Burkholderia cepacia / isolation & purification*
  • Chronic Disease
  • Humans
  • Male
  • Otitis Media, Suppurative / complications*