Inherited deficiency of the second component of complement (C2) with membranoproliferative glomerulonephritis

Am J Med. 1977 May;62(5):765-71. doi: 10.1016/0002-9343(77)90881-6.

Abstract

The occurrence of membranoproliferative glomerulonephritis in a 13 year old boy with inherited complete deficiency of the second component of complement (C2) is described here for the first time. Results of the complement studies and the associations of glomerulonephritis with complement deficiencies are discussed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Complement C1 / analysis
  • Complement C2 / deficiency*
  • Complement C3 / analysis
  • Complement C4 / analysis
  • Complement C5 / analysis
  • Complement System Proteins / deficiency*
  • Glomerulonephritis / complications*
  • Glomerulonephritis / immunology
  • Glomerulonephritis / pathology
  • Humans
  • Kidney Glomerulus / pathology
  • Male

Substances

  • Complement C1
  • Complement C2
  • Complement C3
  • Complement C4
  • Complement C5
  • Complement System Proteins