Budding yeast morphogenesis: signalling, cytoskeleton and cell cycle

Curr Opin Cell Biol. 1995 Dec;7(6):845-55. doi: 10.1016/0955-0674(95)80069-7.


Yeast-like fungi such as Saccharomyces cerevisiae exhibit a range of cell types differing in cell shape, gene expression and growth pattern. Signal transduction pathways mediate transitions between different cell types. Nutritional signals induce rounded yeast-form cells either to enter invasive growth as elongated filamentous cells or to arrest to prepare for stationary phase, conjugation, or meiosis. An emerging theme is that development critically depends upon differential regulation of vegetative functions, including cytoskeletal organization and cell cycle progression, as much as on the expression of cell type specific gene products.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Cycle / physiology*
  • Cytoskeleton / physiology*
  • Morphogenesis / physiology
  • Signal Transduction / physiology*
  • Yeasts / cytology*
  • Yeasts / physiology