Long-term results of percutaneous transluminal angioplasty in renovascular hypertension

Acta Radiol. 1996 Jan;37(1):36-40. doi: 10.1177/02841851960371P107.

Abstract

Purpose: The long-term effect of percutaneous transluminal renal angioplasty (PTRA) was assessed in 50 patients with renovascular hypertension.

Material and methods: Thirty-eight of the patients had atherosclerotic disease and 12 patients fibromuscular dysplasia (FMD). Dilatation with a balloon catheter were performed at 6 to 8 atm for 15 to 30 s.

Results: PTRA was technically successful in 46 (92%) patients. Three of the failures underwent surgical revascularization. There was no mortality connected with PTRA. Minor complications occurred in 6 (12%) patients, and surgical intervention was required in 1. In 4 patients with restenosis, repeated PTRA was performed in 2, and surgery in the other 2 patients. Bilateral disease occurred in 12 patients, and 3 had sequential bilateral PTRA. In 9 patients with atherosclerotic ostial stenosis, PTRA was technically successful in 8 (89%). Thirty-eight patients were re-examined with a mean follow-up of 4 years. At follow-up, 5 (45%) of the patients with FMD were classified as cured, 6 (55%) as improved, and none as failed. In the 27 patients with atherosclerotic disease, 23 (85%) had long-term benefit, 3 (11%) were cured, 20 (74%) were improved, and 4 (15%) were failures. In the 8 patients with ostial atherosclerotic lesions and successful PTRA, there was a 75% long-term benefit. Two patients died during follow-up, both from myocardial infarction.

Conclusion: The result suggest that PTRA is effective in long-term management of renovascular hypertension, not only in patients with fibromuscular stenosis, but also in patients with atherosclerotic disease, even when ostial lesions are present.

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon* / adverse effects
  • Angioplasty, Balloon* / statistics & numerical data
  • Arteriosclerosis / complications
  • Arteriosclerosis / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension, Renovascular / complications
  • Hypertension, Renovascular / therapy*
  • Male
  • Middle Aged
  • Renal Artery Obstruction / complications
  • Renal Artery Obstruction / therapy
  • Renal Artery*
  • Time Factors
  • Treatment Outcome