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Case Reports
, 10 (1), 73-5

Nephrotic Syndrome in a Mother and Her Infant: Relationship With Cytomegalovirus Infection

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Case Reports

Nephrotic Syndrome in a Mother and Her Infant: Relationship With Cytomegalovirus Infection

M Giani et al. Pediatr Nephrol.

Abstract

This case report describes infantile nephrotic syndrome (NS) in a baby girl with a clinically severe cytomegalovirus (CMV) infection. Culture of the baby's urine was positive for CMV and IgM anti-CMV antibodies were detected. After an unsuccessful course of corticosteroids, gancyclovir treatment was started and a remission of cutaneous, pulmonary, and renal symptoms was achieved. As the mother also developed NS at the end of pregnancy, a common etiology could be postulated, although there were no signs of recent CMV infection in the mother, only anti-CMV IgG. The relationship between CMV infection and glomerular disease is still unclear; NS may represent another manifestation of CMV disease.

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Cited by 5 PubMed Central articles

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