Human minisatellite mutation rate after the Chernobyl accident

Nature. 1996 Apr 25;380(6576):683-6. doi: 10.1038/380683a0.


Germline mutation at human minisatellite loci has been studied among children born in heavily polluted areas of the Mogilev district of Belarus after the Chernobyl accident and in a control population. The frequency of mutation was found to be twice as high in the exposed families as in the control group. Mutation rate in the Mogilev families was correlated with the level of caesium-137 surface contamination, consistent with radiation induction of germline mutation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cesium Radioisotopes
  • Cohort Studies
  • DNA Fingerprinting
  • DNA Probes
  • DNA, Satellite / genetics
  • DNA, Satellite / radiation effects*
  • Female
  • Germ-Line Mutation
  • Humans
  • Infant
  • Male
  • Mutation*
  • Power Plants*
  • Radioactive Fallout
  • Radioactive Hazard Release*
  • Ukraine


  • Cesium Radioisotopes
  • DNA Probes
  • DNA, Satellite
  • Radioactive Fallout