High levels of genetic change in rodents of Chernobyl

Nature. 1996 Apr 25;380(6576):707-8. doi: 10.1038/380707a0.

Abstract

Base-pair substitution rates for the mitochondrial cytochrome beta gene of free-living, native populations of voles collected next to reactor 4 at Chernobyl, Ukraine, were estimated by two independent methods to be in excess of 10(-4) nucleotides per site per generation. These estimates are hundreds of times greater than those typically found in mitochondria of vertebrates, suggesting that the environment resulting from this nuclear power plant disaster is having a measurable genetic impact on the organisms of that region. Despite these DNA changes, vole populations thrive and reproduce in the radioactive regions around the Chernobyl reactor.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Retracted Publication

MeSH terms

  • Animals
  • Arvicolinae / genetics*
  • Cytochrome b Group / genetics
  • Embryo, Mammalian
  • Female
  • Genetic Variation
  • Molecular Sequence Data
  • Mutation*
  • Power Plants*
  • Pregnancy
  • Radioactive Hazard Release*
  • Ukraine

Substances

  • Cytochrome b Group

Associated data

  • GENBANK/U54472
  • GENBANK/U54473
  • GENBANK/U54474
  • GENBANK/U54475
  • GENBANK/U54476
  • GENBANK/U54477
  • GENBANK/U54478
  • GENBANK/U54479
  • GENBANK/U54480
  • GENBANK/U54481
  • GENBANK/U54482
  • GENBANK/U54483
  • GENBANK/U54484
  • GENBANK/U54485
  • GENBANK/U54486
  • GENBANK/U54487
  • GENBANK/U54488
  • GENBANK/U54489
  • GENBANK/U54490
  • GENBANK/U54491
  • GENBANK/U54492
  • GENBANK/U54493
  • GENBANK/U54494
  • GENBANK/U54495