Procalcitonin as a marker for the early diagnosis of neonatal infection

J Pediatr. 1996 Apr;128(4):570-3. doi: 10.1016/s0022-3476(96)70374-8.


Serum procalcitonin was determined in newborn infants at the time of admission to the pediatrics or obstetrics unit. Increased levels were found in all neonates with bacterial sepsis. Neonates with viral infection, bacterial colonization, or neonatal distress had normal or slightly increased levels. These data suggest that procalcitonin might be of value in diagnosing neonatal sepsis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Infections / blood
  • Biomarkers / blood
  • Calcitonin / blood*
  • Calcitonin Gene-Related Peptide
  • Glycoproteins / blood*
  • Humans
  • Infant, Newborn
  • Prospective Studies
  • Protein Precursors / blood*
  • Sepsis / blood*
  • Virus Diseases / blood


  • Biomarkers
  • CALCA protein, human
  • Glycoproteins
  • Protein Precursors
  • Calcitonin
  • Calcitonin Gene-Related Peptide