Mechanism of action of rapamycin (Sirolimus, Rapamune)

Transplant Proc. 1996 Apr;28(2):964-9.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antibiotics, Antineoplastic / pharmacology*
  • Carrier Proteins / metabolism
  • Cattle
  • Cell Cycle / drug effects
  • Cell Division / drug effects
  • Cytokines / biosynthesis
  • DNA-Binding Proteins / metabolism
  • Heat-Shock Proteins / metabolism
  • Humans
  • Immunosuppressive Agents / pharmacology*
  • Lymphocyte Activation / drug effects*
  • Mice
  • Polyenes / pharmacology*
  • Sirolimus
  • T-Lymphocytes / immunology*
  • Tacrolimus Binding Proteins
  • Tumor Cells, Cultured

Substances

  • Antibiotics, Antineoplastic
  • Carrier Proteins
  • Cytokines
  • DNA-Binding Proteins
  • Heat-Shock Proteins
  • Immunosuppressive Agents
  • Polyenes
  • Tacrolimus Binding Proteins
  • Sirolimus