Effects of background light on the human dark-adapted electroretinogram and psychophysical threshold

J Opt Soc Am A Opt Image Sci Vis. 1996 Mar;13(3):601-12. doi: 10.1364/josaa.13.000601.

Abstract

We compared the effects of background light on the sensitivities of two components of the human electroretinogram, the cornea-negative scotopic threshold response (STR) and the cornea-positive PII (beta wave), as well as on the psychophysical sensitivity in a ganzfeld. The background illuminance necessary to reduce the STR (an inner retinal signal) measurably was approximately five times greater than that needed to raise the psychophysical threshold. A background illuminance at least 1 log unit greater still was needed to reduce PII (a signal-reflecting activity of bipolar cells). These findings suggest (1) that the weakest backgrounds that reduce retinal sensitivity have their effect at a site that is proximal to the bipolar cells, a site that involves amacrine or ganglion cells, and (2) that very weak backgrounds have their effect on visual sensitivity at a site more proximal than the scotopic threshold response generator and perhaps more central than the retina.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Dark Adaptation*
  • Electroretinography*
  • Humans
  • Light*
  • Middle Aged
  • Psychophysics* / methods
  • Sensory Thresholds*
  • Time Factors