High pressure effects on protein structure and function

Proteins. 1996 Jan;24(1):81-91. doi: 10.1002/(SICI)1097-0134(199601)24:1<81::AID-PROT6>3.0.CO;2-R.

Abstract

Many biochemists would regard pressure as a physical parameter mainly of theoretical interest and of rather limited value in experimental biochemistry. The goal of this overview is to show that pressure is a powerful tool for the study of proteins and modulation of enzymatic activity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biophysics / methods
  • DNA / metabolism
  • Hydrogen Bonding
  • Hydrostatic Pressure*
  • Models, Molecular
  • Molecular Structure
  • Protein Conformation*
  • Protein Denaturation
  • Proteins / chemistry*
  • Proteins / metabolism
  • Structure-Activity Relationship
  • Temperature

Substances

  • Proteins
  • DNA