Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement

Radiology. 1996 Apr;199(1):241-7. doi: 10.1148/radiology.199.1.8633152.


Purpose: To determine the efficacy of percutaneous vertebroplasty in treating spinal metastases that result in pain or instability.

Materials and methods: Thirty-seven patients (20 men, 17 women; aged 33-86 years) underwent 52 percutaneous injections of surgical cement into a vertebra (vertebroplasty) with fluoroscopic guidance in 40 procedures. Vertebroplasty was performed for analgesia in 29 procedures, stabilization of the vertebral column in five procedures, and both in six procedures.

Results: Twenty-four of the 33 procedures performed for analgesia that were evaluated resulted in clear improvement; seven, moderate improvement; and two, no improvement. Improvement was stable in 73% of patients at 6 months. In the procedure performed for stabilization, no displacement of treated vertebrae was observed (mean follow-up, 13 months). Three patients had transient radiculopathy due to cement extrusion, and two patients had transient difficulty in swallowing.

Conclusion: Vertebroplasty of metastases is a minimally invasive procedure that provides immediate and long-term pain relief and contributes to spinal stabilization.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Cements / therapeutic use*
  • Cervical Vertebrae*
  • Combined Modality Therapy
  • Female
  • Fluoroscopy
  • Humans
  • Injections, Spinal
  • Lumbar Vertebrae*
  • Male
  • Methylmethacrylates / administration & dosage*
  • Methylmethacrylates / therapeutic use
  • Middle Aged
  • Palliative Care / methods*
  • Spinal Neoplasms / secondary*
  • Spinal Neoplasms / therapy*
  • Thoracic Vertebrae*
  • Treatment Outcome


  • Bone Cements
  • Methylmethacrylates