High-dose oral dexamethasone therapy for chronic childhood idiopathic thrombocytopenic purpura

J Pediatr. 1996 Feb;128(2):281-3. doi: 10.1016/s0022-3476(96)70410-9.


Because high-dose oral dexamethasone therapy has been reported to be effective for adults with idiopathic thrombocytopenic purpura, we assessed the short-term efficacy and toxicity of dexamethasone in seven children with chronic or refractory idiopathic thrombocytopenic purpura. Dexamethasone therapy was effective and well tolerated; further long-term studies are warranted.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Dexamethasone / administration & dosage
  • Dexamethasone / adverse effects
  • Dexamethasone / therapeutic use*
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Platelet Count
  • Purpura, Thrombocytopenic / drug therapy*


  • Anti-Inflammatory Agents
  • Dexamethasone