Remifentanil: a new opioid

J Clin Anesth. 1995 Nov;7(7):558-63. doi: 10.1016/0952-8180(95)00127-1.


Remifentanil appears to have pharmacodynamic properties similar to other potent mu opioid agonists. It does, however, have unique pharmacokinetic properties, with a rapid onset and rapid offset of effect, irrespective of the duration of its administration. With this property, remifentanil appears to be a very titratable opioid that will make it suitable for administration for either very brief periods, in which analgesia is required, or over prolonged periods, without the concern for prolonged recovery.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid* / administration & dosage
  • Analgesics, Opioid* / chemistry
  • Analgesics, Opioid* / pharmacokinetics
  • Analgesics, Opioid* / pharmacology
  • Animals
  • Humans
  • Piperidines* / administration & dosage
  • Piperidines* / chemistry
  • Piperidines* / pharmacokinetics
  • Piperidines* / pharmacology
  • Remifentanil


  • Analgesics, Opioid
  • Piperidines
  • Remifentanil