[Initiation of DNA Replication in Streptomyces; Organizational Comparison of the oriC Region in Prokaryotic Organisms]

Postepy Hig Med Dosw. 1995;49(1):149-60.
[Article in Polish]


DnaA protein and its binding sequence (DnaA-box) are two elements essential for the initiation of chromosomal replication in Escherichia coli and other bacteria. Recently these two elements have been found to be conserved in four Gram-positive bacteria (Bacillus subtilis, Micrococcus luteus, Mycoplasma capricolum and Streptomyces lividans). The structures of eubacterial DnaA-box regions and their locations on the chromosome and than functional aspects od DnaA protein have been compared.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / genetics
  • Bacterial Proteins / genetics*
  • DNA Replication / physiology*
  • DNA-Binding Proteins / genetics*
  • Gram-Positive Bacteria / genetics
  • Replication Origin
  • Species Specificity
  • Streptomyces / genetics*


  • Bacterial Proteins
  • DNA-Binding Proteins