A class of highly polymorphic tetranucleotide repeats for canine genetic mapping

Mamm Genome. 1996 May;7(5):359-62. doi: 10.1007/s003359900104.

Abstract

We have identified and characterized a new class of polymorphic markers for the canine genome from a simple tetranucleotide repeat sequence, (GAAA)n. Genetic markers derived from this repeat are highly polymorphic compared with other canine microsatellites, yet are stable enough to be useful for following Mendelian inheritance in multigeneration pedigrees. We show further that (GAAA)n repeats are distributed throughout the canine genome and occur with sufficient frequency to be useful in the development of a framework map of the canine genome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Chromosome Mapping / veterinary*
  • Cosmids
  • Dogs / genetics*
  • Female
  • Genetic Markers*
  • Genome
  • Male
  • Microsatellite Repeats*
  • Molecular Sequence Data
  • Pedigree
  • Polymerase Chain Reaction

Substances

  • Genetic Markers

Associated data

  • GENBANK/L78573
  • GENBANK/L78574
  • GENBANK/L78575
  • GENBANK/L78576
  • GENBANK/L78577
  • GENBANK/L78578
  • GENBANK/L78579
  • GENBANK/L78580
  • GENBANK/L78581
  • GENBANK/L78582
  • GENBANK/L78583
  • GENBANK/L78584
  • GENBANK/L78585
  • GENBANK/L78586
  • GENBANK/L78587
  • GENBANK/L78588
  • GENBANK/L78589
  • GENBANK/L78590
  • GENBANK/L78591
  • GENBANK/L78592
  • GENBANK/L78593
  • GENBANK/L78594
  • GENBANK/L78595
  • GENBANK/L78596
  • GENBANK/L78597
  • GENBANK/L78598
  • GENBANK/L78599
  • GENBANK/L78600
  • GENBANK/L78601
  • GENBANK/L78602