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. 1996 Jun;73(12):1560-2.
doi: 10.1038/bjc.1996.294.

The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

H R Scott  1 , D C McMillan, A Crilly, C S McArdle, R Milroy
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Free PMC article

The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

H R Scott et al. Br J Cancer. 1996 Jun.
Free PMC article

Abstract

Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

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