Constrictive bronchiolitis obliterans following gold therapy for psoriatic arthritis

Eur Respir J. 1995 Dec;8(12):2191-3. doi: 10.1183/09031936.95.08122191.

Abstract

A 41 year old male with psoriatic arthritis developed progressive dyspnoea and airflow obstruction following 4 months of intramuscular gold therapy. Open lung biopsy revealed bronchiolitis obliterans of the constrictive type. This case suggests a possible aetiological role for gold in the pathogenesis of constrictive bronchiolitis obliterans, or alternatively an association between psoriatic arthritis and this inflammatory airway condition.

MeSH terms

  • Adult
  • Antirheumatic Agents / adverse effects*
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Psoriatic / drug therapy*
  • Biopsy
  • Bronchiolitis Obliterans / chemically induced*
  • Bronchiolitis Obliterans / complications
  • Bronchiolitis Obliterans / pathology
  • Humans
  • Lung / pathology
  • Male
  • Organogold Compounds

Substances

  • Antirheumatic Agents
  • Organogold Compounds