Engineered RNA-mediated resistance to tomato spotted wilt virus is sequence specific

Mol Plant Microbe Interact. 1996 Jul;9(5):416-8. doi: 10.1094/mpmi-9-0416.

Abstract

Transgenic plants were produced that expressed a wide range of randomly chosen sequences of the tripartite tomato spotted wilt virus (TSWV) RNA genome or its complement. Testing the progenies of these plants revealed that only transgenic expression of N or NS(M) gene sequences resulted in resistance to TSWV.

MeSH terms

  • Capsid / biosynthesis
  • Genome, Viral
  • Immunity, Innate
  • Lycopersicon esculentum / genetics
  • Lycopersicon esculentum / virology*
  • Plant Diseases
  • Plant Viruses / genetics*
  • Plant Viruses / pathogenicity*
  • Plants, Genetically Modified
  • Plants, Toxic
  • RNA Viruses / genetics
  • RNA Viruses / pathogenicity
  • RNA, Viral / biosynthesis*
  • Tobacco
  • Transcription, Genetic
  • Viral Core Proteins / biosynthesis
  • Viral Nonstructural Proteins / biosynthesis

Substances

  • RNA, Viral
  • Viral Core Proteins
  • Viral Nonstructural Proteins