Comparison of occurrence of genetic syndromes in ventricular septal defect with pulmonic stenosis (classic tetralogy of Fallot) versus ventricular septal defect with pulmonic atresia

Am J Cardiol. 1996 Jun 15;77(15):1375-6. doi: 10.1016/s0002-9149(96)00212-3.


Our results confirm that classic TF can be associated with many genetic conditions, but most patients are nonsyndromic. In contrast, children with TF-PA have a high incidence of genetic syndromes, particularly those related to CATCH22 syndrome.

Publication types

  • Comparative Study

MeSH terms

  • Abnormalities, Multiple / epidemiology
  • Abnormalities, Multiple / genetics*
  • Case-Control Studies
  • Child, Preschool
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 22*
  • Female
  • Heart Septal Defects, Ventricular / genetics*
  • Humans
  • Incidence
  • Male
  • Prevalence
  • Pulmonary Atresia / genetics*
  • Syndrome
  • Tetralogy of Fallot / genetics*