Makaluvamines H-M and damirone C from the pohnpeian sponge Zyzzya fuliginosa

J Nat Prod. 1995 Dec;58(12):1861-7. doi: 10.1021/np50126a008.


Seven new pyrroloiminoquinone alkaloids, makaluvamines H-M [19-24] and damirone C[25], together with the known compounds, makaluvamines C[13], D[14], and G[17], were isolated from the sponge Zyzzya fuliginosa collected at Nahpali Island, Pohnpei, Micronesia. The structures of the new compounds were elucidated by interpretation of spectral data. The chemotaxonomic relationships involving the makaluvamines and related pyrroloiminoquinone alkaloids are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Anti-Infective Agents / isolation & purification*
  • Anti-Infective Agents / pharmacology
  • Imidazoles / isolation & purification*
  • Imidazoles / pharmacology
  • Magnetic Resonance Spectroscopy
  • Porifera / chemistry*
  • Quinolines / isolation & purification*
  • Quinolines / pharmacology
  • Spectrophotometry, Infrared


  • Anti-Infective Agents
  • Imidazoles
  • Quinolines
  • damirone C