Guidelines for drug therapy in renal failure

Ann Intern Med. 1977 Jun;86(6):754-83. doi: 10.7326/0003-4819-86-6-754.

Abstract

Five tables are presented that provide guidelines for drug usage in patients with renal insufficiency. The data are derived from the current medical literature. If specific information about a drug is unavailable, emphasis is given to normal pharmacokinetic variables in arriving at recommendations for therapy. Nephrotoxicity of adverse effects in patients with renal disease are noted and adjustments for dialysis suggested.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Kidney Injury / drug therapy*
  • Acute Kidney Injury / metabolism
  • Analgesics / metabolism
  • Anti-Arrhythmia Agents / metabolism
  • Anti-Bacterial Agents / metabolism
  • Antihypertensive Agents / metabolism
  • Diuretics / metabolism
  • Drug-Related Side Effects and Adverse Reactions
  • Humans
  • Hypnotics and Sedatives / metabolism
  • Pharmaceutical Preparations / metabolism*
  • Tranquilizing Agents / metabolism

Substances

  • Analgesics
  • Anti-Arrhythmia Agents
  • Anti-Bacterial Agents
  • Antihypertensive Agents
  • Diuretics
  • Hypnotics and Sedatives
  • Pharmaceutical Preparations
  • Tranquilizing Agents