The long-term outcome of proximal vein thrombosis during pregnancy is not improved by the addition of surgical thrombectomy to anticoagulant treatment

Eur J Vasc Endovasc Surg. 1996 Jul;12(1):31-6. doi: 10.1016/s1078-5884(96)80272-3.

Abstract

Objectives: To compare the long-term outcome for pregnant/puerperal women with iliofemoral venous thrombosis treated either with thrombectomy and additional anticoagulants or with anticoagulants alone.

Design: Retrospective study of two treatment methods.

Materials: Thirty women with iliofemoral venous thrombosis during pregnancy or puerperium were treated with thrombectomy and additional anticoagulants. Twenty-five women, with the same condition, treated with anticoagulants only were obtained from a registry. The mean follow-up time for both groups was 9 years. The patients of the two groups were well matched, had the same risk factor score and were comparable except for duration of symptoms before treatment.

Methods: The follow-up comprised history and clinical examination, colour Duplex ultrasound and venous strain-gauge plethysmography.

Results: Patency of iliac veins, symptoms of chronic venous disease, venous emptying and venous reflux did not differ between the groups. A significant reduction of outflow was found in 20% of the surgically treated patients and 16% of the controls. Impaired muscle pump function was seen in less than half of the patients in both groups.

Conclusions: Surgical thrombectomy does not offer any advantage over anticoagulation treatment alone in the long-term outcome for patients with iliofemoral venous thrombosis during pregnancy or puerperium.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anticoagulants / therapeutic use*
  • Case-Control Studies
  • Combined Modality Therapy
  • Female
  • Femoral Vein* / diagnostic imaging
  • Femoral Vein* / surgery
  • Follow-Up Studies
  • Humans
  • Iliac Vein* / diagnostic imaging
  • Iliac Vein* / surgery
  • Middle Aged
  • Plethysmography
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / diagnostic imaging
  • Pregnancy Complications, Cardiovascular / drug therapy
  • Pregnancy Complications, Cardiovascular / surgery*
  • Puerperal Disorders / diagnostic imaging
  • Puerperal Disorders / drug therapy
  • Puerperal Disorders / surgery
  • Registries
  • Retrospective Studies
  • Thrombectomy*
  • Thrombosis / diagnostic imaging
  • Thrombosis / drug therapy
  • Thrombosis / surgery*
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Vascular Patency

Substances

  • Anticoagulants