Vitamin C and human health--a review of recent data relevant to human requirements

Int J Vitam Nutr Res. 1996;66(1):19-30.


The recent scientific literature indicates that beyond merely protecting against scurvy vitamin C contributes to many aspects of human health. The main areas of research reviewed include: 1. Vitamin C requirements of smokers. The data indicate that the vitamin C requirement of smokers is higher by at least 60 mg per day (up to 140 mg per day) than that of nonsmokers. 2. Important functions of the body, such as immune response, pulmonary function, and iron absorption are related to vitamin C intakes. Daily vitamin C intake of at least 150-200 mg per day enhance these functions. 3. Vitamin C may play critical roles in the prevention of CHD, cancer and cataract. Based on the available data, vitamin C intakes of at least 80-120 mg per day are associated with lowering the risk of these chronic diseases. 4. The literature documents that these and much higher intake levels of vitamin C are safe.

Publication types

  • Review

MeSH terms

  • Ascorbic Acid Deficiency
  • Ascorbic Acid* / administration & dosage
  • Ascorbic Acid* / physiology
  • Ascorbic Acid* / therapeutic use
  • Cardiovascular Diseases / prevention & control
  • Cataract / prevention & control
  • Diet
  • Health Status*
  • Humans
  • Neoplasms / prevention & control
  • Nutrition Policy
  • Nutritional Requirements*


  • Ascorbic Acid