Nifedipine-induced gingival enlargement around dental implants: a clinical report

J Oral Implantol. 1995;21(2):116-20.


Calcium channel-blocking agents are used extensively for the management of cardiovascular conditions, including angina pectoris, coronary artery spasm, cardiac arrhythmias, and hypertension. Gingival overgrowth around natural teeth has been previously reported in the literature with patients taking calcium channel-blocking agents. This clinical report describes hyperplasia of tissues around titanium dental implants in a patient taking Nifedipine along with the multiphasic approach to treating this medication-induced hyperplasia of the peri-implant tissues.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Calcium Channel Blockers / adverse effects*
  • Cats
  • Dental Care for Chronically Ill
  • Dental Implants / adverse effects*
  • Female
  • Gingival Hyperplasia / chemically induced*
  • Gingival Hyperplasia / therapy
  • Humans
  • Hypertension / drug therapy
  • Nifedipine / adverse effects*


  • Calcium Channel Blockers
  • Dental Implants
  • Nifedipine