Review: the effects of antihypertensive agents on serum lipids

Am J Med Sci. 1996 Aug;312(2):76-84. doi: 10.1097/00000441-199608000-00004.

Abstract

Because various antihypertensive drugs adversely affect lipid metabolism, these drugs may increase associated risks for coronary artery disease and thus offset some of the beneficial effects of blood pressure reduction. In this paper the current literature regarding the effects of antihypertensive agents on serum lipids is reviewed. Differing effects of various classes of antihypertensives are assessed to further our understanding of this very important subject.

Publication types

  • Review

MeSH terms

  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic beta-Antagonists / adverse effects
  • Adrenergic beta-Antagonists / pharmacology
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects
  • Angiotensin-Converting Enzyme Inhibitors / pharmacology
  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / classification
  • Antihypertensive Agents / pharmacology*
  • Calcium Channel Blockers / adverse effects
  • Calcium Channel Blockers / pharmacology
  • Coronary Disease / blood
  • Coronary Disease / etiology
  • Diuretics / adverse effects
  • Diuretics / pharmacology
  • Humans
  • Lipids / blood*
  • Lipoproteins / blood
  • Risk Factors

Substances

  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic beta-Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • Calcium Channel Blockers
  • Diuretics
  • Lipids
  • Lipoproteins