Gastrointestinal manifestations of HIV infection

Lancet. 1996 Aug 10;348(9024):379-83. doi: 10.1016/s0140-6736(96)01034-3.


The harrowing picture of emaciated terminally ill AIDS patients is a reminder of our lack of understanding of immunological mechanisms that normally control opportunistic infections. Many gastrointestinal pathogens in patients with AIDS are resistant to treatment and lead inexorably to weight loss and death. Although knowledge of the pathogenesis and clinical significance of weight loss has improved considerably, this has not yet led to a sustained effort to improve nutritional status during early stages of disease.

Publication types

  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections* / drug therapy
  • AIDS-Related Opportunistic Infections* / microbiology
  • AIDS-Related Opportunistic Infections* / physiopathology
  • Animals
  • Cachexia / microbiology
  • Ciprofloxacin / therapeutic use
  • Diarrhea / drug therapy
  • Diarrhea / microbiology*
  • Gastrointestinal Diseases* / microbiology
  • Gastrointestinal Diseases* / physiopathology
  • Humans


  • Ciprofloxacin