Abstract
A 59-year-old man was diagnosed as having constrictive pericarditis 17 months after a typical hydralazine-induced autoimmune syndrome. This late complication of hydralazine has been reported only once. Ten years later the patient was found to have anti-neutrophil cytoplasmic antibodies directed against myeloperoxidase.
MeSH terms
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Antibodies, Antineutrophil Cytoplasmic
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Antihypertensive Agents / adverse effects*
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Antihypertensive Agents / therapeutic use
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Autoantibodies / analysis*
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Autoimmune Diseases / chemically induced*
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Autoimmune Diseases / physiopathology
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Humans
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Hydralazine / adverse effects*
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Hydralazine / therapeutic use
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Hypertension / drug therapy
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Male
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Middle Aged
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Pericarditis, Constrictive / chemically induced*
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Pericarditis, Constrictive / diagnosis
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Peroxidase / immunology
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Thoracotomy
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Time Factors
Substances
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Antibodies, Antineutrophil Cytoplasmic
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Antihypertensive Agents
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Autoantibodies
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Hydralazine
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Peroxidase