Meiosis: how could it work?

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8167-74. doi: 10.1073/pnas.93.16.8167.


A physical connection between homologs is required for reductional segregation at the first division of meiosis. This connection is usually provided by one or a few well-spaced crossovers. A speculative overview of processes leading to formation of these crossovers is presented.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Evolution
  • Cell Cycle
  • Chromosomes / physiology*
  • Chromosomes / ultrastructure
  • Crossing Over, Genetic*
  • Humans
  • Meiosis*
  • Mitosis
  • Plants
  • Prophase
  • Recombination, Genetic*
  • Saccharomyces cerevisiae
  • Synaptonemal Complex / physiology